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个人简介：宋宏彬，解放军疾病预防控制中心副主任、研究员、博士生导师，主要从事传染病防控技术研究，享受国务院政府特殊津贴，入选国家“万人计划”科技创新领军人才、全军高层次科技人才工程拔尖人才和科技北京百名领军人才，是国家创新人才推进计划重点领域创新团队负责人。承担国家重大传染病专项、国家重点研发计划“生物安全关键技术研究”专项和国家自然科学基金等多项课题，以通讯作者在Lancet、Nature Machine Intelligence、Nature communications、Signal transduction and targeted therapy等国际期刊发表SCI论文100余篇，主编译专著8部，获得军队科技进步一等奖2项和二等奖3项。

研究方向：传染病防控技术研究

教育经历：

(1) 1996.08至1999.07，第四军医大学，分子流行病学，博士

(2) 1993.08至1996.07，军事医学科学院，分子流行病学，硕士

(3) 1986.08至1991.07，第三军医大学，预防医学，学士

工作经历：

(1) 2018.11至今，中国人民解放军疾病预防控制中心，传染病防控科，研究员、博士生导师

(2) 2009.09至2018.11，军事医学科学院疾病预防控制所，研究员、博士生导师

(3) 2005.05至2009.09，军事医学科学院疾病预防控制所，副研究员

(4) 2003.04至2005.05，军事医学科学院疾病预防控制所，助理研究员

(5)2001.1至2003.3,美国南卡罗来纳医科大学，博士后

代表性科研项目：

1.病原微生物事件追踪溯源关键技术研究，国家重点研发计划, 2023YFC2605600，2023.11-2026.10，986.08万元，在研，项目负责人

2.基于膜融合DNA纳米笼载体递呈通用双靶点CRISPR-Cas13系统的流感和新冠病毒共清除技术研究，国家自然科学基金，82572574，2026.01-2029.12，48万元，在研，项目负责人

代表性学术论文：

1. Yuqi Liu, Jing Li, Peihan Li,Yehong Yang, Kaiying Wang, Jinhui Li, Lang Yang, Jiangfeng Liu, Leili Jia, Aiping Wu, Juntao Yang, Peng Li,Hongbin Song(通讯作者). ARNLE model identifies prevalence potential of SARS-CoV-2 variants. Nature Machine Intelligence. 2025(7): 18-28. (2025IF: 23.9,中科院1区)

2. Leili Jia, Haihua Luo, Lizhong Li, Mingyao Wang, Jiangfeng Liu, Yuan Liang, Shan Li, Yong Jiang, Juntao Yang,Hongbin Song(通讯作者).Targeting complement hyperactivation: a novel therapeutic approach for severe pneumonia induced by influenza virus/staphylococcus aureus coinfection.Signal Transduction and Targeted Therapy. 2024; 9:51-54. (2024IF: 52.7,中科院1区)

3.Shaofu Qiu, Zhao Chen, Airu Zhu, Qiuhui Zeng, Hongbo Liu, Xiaoqing Liu, Feng Ye, Yingkang Jin, Jie Wu, Chaojie Yang, Qi Wang, Fangli Chen, Lan Chen, Sai Tian, Xinying Du, Qingtao Hu, Jinling Cheng, Canjie Chen, Fang Li, Jing Sun, Yanqun Wang, Jingxian Zhao, Jincun Zhao,Hongbin Song(通讯作者). Successful clearance of persistent SARS-CoV-2 asymptomatic infection following a single dose of Ad5-nCoV vaccine. Signal Transduction and Targeted Therapy. 2023; 8: 123. (2023IF: 40.8,中科院1区)

4. Yawei Wang, Min Wang, Renlong Bao, Ligui Wang, Xinying Du, Shaofu Qiu, Chaojie Yang, Hongbin Song(通讯作者). Journal of Medical Virology. 2023; 95(8): e29026. (2023IF: 12.7,中科院1区)

5.Shaofu Qiu, Kangkang Liu, Chaojie Yang, Ying Xiang, Kaiyuan Min, Kunpeng Zhu, Hongbo Liu, Xinying Du, Mingjuan Yang, Ligui Wang, Yong Sun, Haijian Zhou, Muti Mahe, Jiayong Zhao, Shijun Li, Deshan Yu, Jane Hawkey, Kathryn E. Holt, Stephen Baker, Juntao Yang, Xuebin Xu,Hongbin Song(通讯作者). A Shigella sonnei clone with extensive drug resistance associated with waterborne outbreaks in China. Nature Communications. 2022;13(1): 7365. (2022IF: 17.7,中科院1区)

6.Hongbo Liu; Shuailei Chang; Sijia Chen; Yue Du; Hui Wang; Chao Wang; Ying Xiang; Qi Wang; Zhenjun Li; Shengqi Wang; Shaofu Qiu;Hongbin Song(通讯作者); Highly sensitive and rapid detection of SARS-CoV-2 via a portable CRISPR-Cas13a-based lateral flow assay. Journal of Medical Virology. 2022;94(12): 5858-5866. (2022IF: 20.7,中科院1区)

7. HongBo Liu, Qingfeng Li, Ying Xiang, Hong Li, Kangkang Liu, Xinying Du, Chaojie Yang, Hongbo Liu, Mengjing Shi, Xueqian Hu, Hui Wang, Xiaohong Zhang, Xiangda Li, Sai Tian, Renlong Bao, Ligui Wang, Shaofu Qiu,Hongbin Song(通讯作者). An outbreak of acute respiratory disease caused by HAdV-55 in Beijing, China, 2020. Journal of Medical Virology. 2022; 94(12):5858-5866. (2022IF: 20.7,中科院1区)

8. Yi Yang, Rongtao Zhao, Yule Wang, Dan Song, Bo Jiang, Xudong Guo, Wanying Liu, Feng Long,Hongbin Song(通讯作者), Rongzhang Hao. Rapid and universal detection of SARS-CoV-2 and influenza A virus using a reusable dual-channel optic fiber immunosensor. Journal of Medical Virology. 2022; 94(11): 5325-5335. (2022IF: 20.7,中科院1区)

9.Wang S., Li H., Kou Z., Ren F., Jin Y., Yang L., Dong X., Yang M., Zhao J., Liu H., Dong N., Jia L., Chen X., Zhou Y., Qiu S., Hao R.,Song H.(通讯作者). Highly sensitive and specific detection of hepatitis B virus DNA and drug resistance mutations utilizing the PCR-based CRISPR-Cas13a system. Clinical Microbiology and Infection. 2021; 27(3): 443-450. (2021IF：13.3，中科院1区)

10. Hongbo Liu, Hao Li, Yuan Liang, Xinying Du, Chaojie Yang, Lang Yang, Jing Xie, Rongtao Zhao, Yigang Tong, Shaofu Qiu,Hongbin Song(通讯作者). Phage-delivered sensitisation with subsequent antibiotic treatment reveals sustained effect against antimicrobial resistant bacteria. Theranostics. 2020;10(14):6310-6321. (2020IF: 11.6,中科院1区)

其他学术、教学成果：

（一）主编专著

1.《传染病信息学概论》，科学出版社

2.《医学大数据分析挖掘技术与应用》，科学出版社

3.《卫生监督技术及应用》，军事医学科学出版社

4.《流行病学研究相关软件应用》，军事医学科学出版社

5.《卫生杀虫药械评价与应用》，军事医学科学出版社

（二）国家发明专利

1.宋宏彬;邱少富;刘鸿博;李浩;梁媛;杨超杰;赵荣涛;贾雷立;李鹏;王立贵.一种使用温和噬菌体载体包装CRISPR-Cas9系统的方法,中国, CN201710688906.0

2.宋宏彬;李浩;邱少富;生春雨;杨超杰;刘鸿博;王珊;贾雷立;谢靖;王立贵;李鹏.孙岩松;rAAV8-CRISPR-SaCas9系统在制备乙肝治疗药物中的应用,中国, 201710688779.4

3.宋宏彬;邱少富;刘鸿博;李浩;梁媛;杨超杰;赵荣涛;贾雷立;李鹏;王立贵.一种靶向清除细菌耐药性质粒的CRISPR-Cas9系统及应用,中国, CN201710688895.6

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