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卫生毒理学系
朱华龙
发布日期
2025-10-22
浏览人数
3933

个人简介:朱华龙,1992年生,医学博士,校聘副教授,安徽省教育厅优青,硕士研究生导师。20226月博士毕业于安徽医科大学。主要研究方向为:环境毒物与生殖发育毒理学。主持国家自然科学基金青年项目1项、安徽省优青项目1项、省教育厅重点项目1项,指导国家级大创1项和安徽医科大学研究生科研与实践创新项目3项,参与国家自然科学基金2项、国家重点研发计划子课题1项和安徽省杰青项目。获得国家发明专利2项、安徽省自然科学科技奖一项、安徽省教学成果二等奖1项和国家级及以上学术会议报告奖3项。以第一/通讯作者在Nat CommunAdv. SciRedox BiolJ Hazad MaterEnviron IntSci Total Environ等国际知名杂志发表SCI论文18篇(IF107篇;中科院1区论文11篇)。

研究方向:发育毒理学

教育经历:

2017-092022-07,安徽医科大学,卫生毒理学,硕博连读;

2012-092017-07,安徽医科大学,预防医学(妇幼卫生方向),本科。

工作经历:

2022-07至今,安徽医科大学,公共卫生学院,副教授,硕士生导师。

2025-06至今,美国堪萨斯大学医学中心,博士后


代表性科研项目:

(1)国家自然科学基金委员会,青年科学基金项目, 82304181, ATF5依赖的线粒体逆行响应在镉诱导胎盘细胞焦亡中的作用及其机制, 2024-01-012026-12-31, 30万元,在研,主持;

(2)安徽省教育厅,优秀青年项目,2024AH030024,胎源性不育症的环境病因机制研究,2025-012027-12, 50万元,在研,主持。

(3)安徽省教育厅,重点项目, 2022AH050644,孕期母体镉暴露抑制子代睾丸睾酮合成的胎盘病因机制, 2023-012024-12, 10万元,在研,主持。


代表性学术论文(#第一作者,*通讯作者):

1.Zhu, Hua-Long#; Dai, Li-Min; Xiong, Yong-Wei; Shi, Xue-Ting; Liu, Wei-Bo; Fu, Yi-Ting; Zhou, Guo-Xiang; Zhang, Shuang; Gao, Lan; Zhang, Cheng; Zhao, Ling-Li; Xu, Xiao-Feng; Huang, Yi-Chao; Xu, De-Xiang; Wang, Hua*; Gestational exposure to environmental cadmium induces placental apoptosis and fetal growth restriction via Parkin-modulated MCL-1 degradation,Journal of Hazardous Materials, 2022, 424: 127268. (2024 IF11.3,中科院1)

2.Zhu, Hua-Long#; Shi, Xue-Ting; Xu, Xiao-Feng; Zhou, Guo-Xiang; Xiong, Yong-Wei; Yi, Song-Jia; Liu, Wei-Bo; Dai, Li-Min; Cao, Xue-Lin; Xu, De-Xiang*; Wang, Hua*; Melatonin protects against environmental stress-induced fetal growth restriction via suppressing ROS-mediated GCN2/ATF4/BNIP3-dependent mitophagy in placental trophoblasts,Redox Biology, 2021, 40: 101854. (2024 IF10.6,中科院1)

3.Zhu, Hua-Long#; Shi, Xue-Ting#; Xu, Xiao-Feng#; Xiong, Yong-Wei; Yi, Song-Jia; Zhou, Guo-Xiang; Liu, Wei-Bo; Huang, Miao-Miao; Gao, Lan; Zhang, Cheng; Zhao, Ling-Li; Xu, De-Xiang*; Wang, Hua*; Environmental cadmium exposure induces fetal growth restriction via triggering PERK-regulated mitophagy in placental trophoblasts, Environment International, 2021, 147: 106319. (2024 IF10.3,中科院1)

4.Zhu, Hua-Long#; Xu, Xiao-Feng#; Shi, Xue-Ting; Feng, Yu-Jie; Xiong, Yong-Wei; Nan, Yuan; Zhang, Cheng; Gao, Lan; Chen, Yuan-Hua; Xu, De-Xiang; Wang, Hua*; Activation of autophagy inhibits cadmium-triggered apoptosis in human placental trophoblasts and mouse placenta,Environmental Pollution, 2019, 254: 112991. (2024 IF8.1,中科院2)

5. Xiong, Yong-Wei#;Zhu, Hua-Long#; Zhang, Jin#; Geng, Hao#; Tan, Lu-Lu; Zheng, Xin-Mei; Li, Hao; Fan, Long-Long; Wang, Xin-Run; Zhang, Xu-Dong; Wang, Kai-Wen; Chang, Wei; Zhang, Yu-Feng; Yuan, Zhi; Duan, Zong-Liu; Cao, Yun-Xia; He, Xiao-Jin*; Xu, De-Xiang*; Wang, Hua*; Multigenerational paternal obesity enhances the susceptibility to male subfertility in offspring via Wt1 N6-methyladenosine modification,Nature Communications, 2024, 15(1): 1353. (2024IF15.7,中科院1)

6.Ye-Xin, Luo#;Zhu, Hua-Long#; Huang, Bin-Bin#; Sun, Cheng-Fang; Zhang, Xin-Xin; Wang, Xin-Run; Hu, Yi-Fan;Zhang, Xu-Dong; Xu, Shen-Dong; Zhou, Huang; Pan, Rui; Chang, Wei; Yuan, Zhi; Xiong Yong-Wei; Xu, Xiao-Feng; Zhao, Ling-Li; Xu, De-Xiang; Wang, Hua*; Placental RTN3L-dependent ER-Phagy Contributes to Fetal Testicular Dysplasia Upon Environmental Stress,Advanced science,2025 Apr 26: e2500924. (2024IF14.1,中科院1)

7.Wang, Tian-Tian#;Zhu, Hua-Long#; Ouyang, Kong-Wen#; Wang, Hua; Ye-Xin, Luo; Zheng, Xin-Mei; Ling, Qing; Wang, Kai-Wen; Zhang, Jin; Chang, Wei; Lu, Qi; Zhang, Yu-Feng; Yuan, Zhi; Li, Hao; Xiong, Yong-Wei; Wei, Tian; Wang, Hua*; Environmental cadmium inhibits testicular testosterone synthesis via Parkin-dependent MFN1 degradation,Journal of Hazardous Materials, 2024, 470: 134142.(2024 IF11.3,中科院1)

8. Du, Zun-Yu#;Zhu, Hua-Long#; Chang, Wei#; Zhang, Yu-Feng; Ling, Qing; Wang, Kai-Wen; Zhang, Jin; Zhang, Quan-Bing; Kan, Xiu-Li; Wang, Qu-Nan; Wang, Hua*; Zhou, Yun*; Maternal prednisone exposure during pregnancy elevates susceptibility to osteoporosis in female offspring: The role of mitophagy/FNDC5 alteration in skeletal muscle,Journal of Hazardous Materials, 2024, 469: 133997. (2024 IF11.3,中科院1)

9.Ouyang, Kong-Wen#; Wang, Tian-Tian#; Wang, Hua; Luo, Ye-Xin; Hu, Yi-Fan; Zheng, Xin-Mei; Ling, Qing; Wang, Kai-Wen; Xiong, Yong-Wei; Zhang, Jin; Chang, Wei; Zhang, Yu-Feng; Yuan, Zhi; Li, Hao; Gao, Lan; Xu, De-Xiang;Zhu, Hua-Long*; Yang, Lan*; Wang, Hua*; m6A-methylated Lonp1 drives mitochondrial proteostasis stress to induce testicular pyroptosis upon environmental cadmium exposure.”Science of the Total Environment, 2024, 931: 172938. (2024 IF8. 0,中科院1)

10.Zhang, Yu-Feng#;Zhu, Hua-Long#;Xu, Xiao-Feng#; Zhang, Jin; Ling, Qing; Zhang, Shuang; Chang, Wei;Xiong, Yong-Wei; Xu, De-Xiang; Wang, Hua*; Activation of Atg5-dependent placental lipophagy ameliorates cadmium-induced fetal growth restriction,Environmental Pollution, 2023, 328: 121602. (2024 IF8.1,中科院2)


其他学术、教学成果:

1.获得安徽省自然科学技术奖和教学成果奖:

1)安徽省自然科学技术三等奖,王华、徐德祥、朱华龙、熊永伟、许孝凤,环境源性糖尿病前期的胎盘-胎肝发育损伤机制及干预研究,2023

2)安徽省研究生教学成果二等奖,第13, 打造质量结构双优型双师队伍,培养高水平实战型公共卫生人才,2024

2.获得国家发明专利:

1)一种雄性不育症小鼠模型的构建方法,国家发明专利,2022-07-22, CN202210100169.9

2)一种父源性认知障碍动物模型的构建方法及其应用,国家发明专利,2023-11-25, CN202210861165.2


联系方式:zhuhualongdev@126.com


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