唐人阁trg最新论坛,诚中村凤楼,一品楼免费论坛,栖凤楼发布信息交流

个人简介：医学博士，二级教授，博士生导师，安徽省首批学术和技术带头人。兼任中华预防医学会常务理事、安徽省预防医学会会长。主持国家自然科学基金面上项目7项。在Science of The Total Environment、Oncogene、Ecotoxicology and Environmental Safety、Toxicology和中华劳动卫生与职业病杂志等国内外学术期刊发表论文百余篇。获省级科学技术二等奖一项，三等奖四项，获中华医学会“新中国六十年医疗卫生事业杰出贡献奖”。担任《安徽预防医学杂志》编委会主任，《安徽医科大学学报》、《中华疾病控制杂志》和《职业卫生与应急救援》副主编。担任全国医药高等院校规划教材《卫生学》（临床医学本科，第8版、第9版）主编、全国医药高等院校规划教材《预防医学》（护理本科，第1版）主编、全国医药高等院校规划教材《职业卫生与职业医学》（预防医学本科，第8版）副主编，全国住院医师规范化培训规划教材《预防医学》（第1版、第2版）主编。

研究方向：职业毒理学、皮肤毒理学

代表性科研项目：

1.国家自然科学基金面上项目（批准号：82173494），起止年月：2022/01-2025/12;

2.国家自然科学基金面上项目（批准号：81874259），起止年月：2019/01-2022/12;

3.国家自然科学基金面上项目（批准号：81673141），起止年月：2017/01-2020/12；

4.国家自然科学基金面上项目（批准号：81371730），起止年月：2014/01-2017/12；

5.国家自然科学基金面上项目（批准号：30872147），起止年月：2009/01-2011/12；

6.国家自然科学基金面上项目（批准号：30671787），起止年月：2007/01-2009/12；

7.国家自然科学基金面上项目（批准号：30471469），起止年月：2005/01-2007/12。

代表性学术论文：

[1]Liu Z, Ma J, Zuo X, Zhang X, Xie H, Wang F, Wu C, Zhang J, Zhu Q. IP3R-dependent mitochondrial dysfunction mediates C5b-9-induced ferroptosis in trichloroethylene-caused immune kidney injury. Front Immunol, 2023,14:1106693.

[2]Zhang X, Xie H, Liu Z, Zhang J, Deng L, Wu Q, Duan Y, Wang F, Wu C, Zhu Q. HMGB 1 acetylation mediates trichloroethylene-induced immune kidney injury by facilitating endothelial cell-podocyte communication. Ecotoxicol Environ Saf, 2023,259:115042.

[3]Zhou S, Wang Z, Gao L, Chen M, Duan Y, Zhou P, Liu Z, Wu C, Zhang J, Zhu Q. C5a/C5aR1 axis as a key driver promotes epithelial-to-mesenchymal transition in airway epithelial cells in silica nanoparticles-induced pulmonary fibrosis. Int Immunopharmacol, 2023,125(Pt B):111112.

[4]Wang F, Hong Y, Jiang W, Wang Y, Chen M, Zang D, Zhu Q. ROS-mediated inflammatory response in liver damage via regulating the Nrf2/HO-1/NLRP3 pathway in mice with trichloroethylene hypersensitivity syndrome. J Immunotoxicol, 2022,19(1):100-108.

[5]Zhang X, Duan Y, Ma J, Liu Z, Ding Y, Xie H, Peng J, Wang F, Zhang J, Zhu Q. Trichloroethylene induces immune renal tubular injury through SIRT 1/HSP 70/TLR 4 pathway in BALBc mice. Int Immunopharmacol, 2022,112:109203.

[6]Xie H, Peng J, Zhang X, Deng L, Ding Y, Zuo X, Wang F, Wu Y, Zhang J, Zhu Q. Effects of mitochondrial reactive oxygen species-induced NLRP3 inflammasome activation on trichloroethylene-mediated kidney immune injury. Ecotoxicol Environ Saf, 2022,244:114067.

[7]Liu Z, Ma J, Zuo X, Zhang X, Hong Y, Cai S, Huang H, Wang F, Wu C, Zhang J, Zhu Q. C5b-9 mediates ferroptosis of tubular epithelial cells in trichloroethylene-sensitization mice. Ecotoxicol Environ Saf, 2022,244:114020.

[8]Zuo X, Liu Z, Ma J, Ding Y, Cai S, Wu C, Zhang J, Zhu Q. Wnt 5a mediated inflammatory injury of renal tubular epithelial cells dependent on calcium signaling pathway in Trichloroethylene sensitized mice. Ecotoxicol Environ Saf, 2022,243:114019.

[9]Wang F, Huang M, Wang Y, Hong Y, Zang D, Yang C, Wu C, Zhu Q. Membrane Attack Complex C5b-9 Promotes Renal Tubular Epithelial Cell Pyroptosis in Trichloroethylene-Sensitized Mice. Front Pharmacol, 2022,13:877988.

[10]Zhang JX, Yang Y, Huang H, Xie HB, Huang M, Jiang W, Ding BW, Zhu QX. TNF-α/TNFR1 regulates the polarization of Kupffer cells to mediate trichloroethylene-induced liver injury. Ecotoxicol Environ Saf, 2022,230:113141.

[11]Ma J, Liu Z, Zhou S, Chen M, Gao L, Zuo X, Zhang X, Zhang J, Zhu Q. Renal tubular in TCE-sensitization-induced immune kidney injury: Role of mitochondrial DNA in activating the cGAS-STING signaling pathway. Int Immunopharmacol, 2022 ,113(Pt B):109432.

[12]Wang F, Dai Y, Huang M, Zhang C, Huang L, Wang H, Ye L, Wu Q, Zhang X, Zhu Q. Glomerular Damage in Trichloroethylene-Sensitized Mice: Targeting Cathepsin L-Induced Hyperactive mTOR Signaling. Front Pharmacol. 2021 Jul 29;12:639878.

[13]Wang Y, Huang M, Du X, Hong Y, Huang L, Dai Y, Wu Q, Wang F, Zhu Q. Renal tubular cell necroptosis: A novel mechanism of kidney damage in trichloroethylene hypersensitivity syndrome mice. J Immunotoxicol, 2021,18(1):173-182.

[14]Xie H, Yang L, Yang Y, Jiang W, Wang X, Huang M, Zhang J, Zhu Q. C5b-9 membrane attack complex activated NLRP3 inflammasome mediates renal tubular immune injury in trichloroethylene sensitized mice. Ecotoxicol Environ Saf, 2021,208:111439.

[15]Xie H, Wang H, Wu Q, Peng J, Huang H, Wang Y, Huang M, Jiang W, Yang Y, Zhang X, Zhang J, Zhu Q. Endothelin-1/Endothelin Receptor Type A-Angiopoietins/Tie-2 Pathway in Regulating the Cross Talk Between Glomerular Endothelial Cells and Podocytes in Trichloroethylene-Induced Renal Immune Injury. J Inflamm Res,2021 ,14:761-776.

[16]Ruan L, Yang P, Chen SP, Wu C, Zhu Q. Vitamin E attenuates the development of bleomycin-induced skin fibrosis in mice. Australas J Dermatol, 2021 ,62(2):e298-e300.

联系方式：0551-62923009