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个人简介：

沈彤，医学博士，教授、博士生导师、博士后合作导师，澳大利亚昆士兰科技大学（QUT）访问学者，安徽省学术和技术带头人后备人选，安徽省高校拔尖人才，安徽医科大学东南学者特聘教授。现任安徽医科大学公共卫生学院职业卫生与环境卫生学系主任、重大慢病与环境可控研究科研创新团队带头人。兼任中国环境诱变剂学会常务理事、中国职业安全健康协会工业防毒专委会副主委、安徽省环境诱变剂学会理事长、安徽省预防医学会常务理事兼职业卫生与职业病专委会主任委员、全国公共卫生与预防医学名词编委会环境卫生学名词编写分会委员、安徽省环境应急专家。

主编、副主编、参编规划教材10余部，人民卫生出版社国家级规划教材五年制临床医学专业《预防医学》（第8版）副主编，预防医学专业《职业卫生与职业医学》（第9版）编委，教育部公共卫生与预防医学“101计划”核心教材《环境与健康》编委，护理专业《预防医学》（第五版）编委，省级规划教材《预防保健学》（第4版）主编。安徽省省级一流课程《职业卫生与职业医学》负责人，获安徽省教学成果奖4项。已建立万人以上的职业人群健康研究随访队列，利用多组学技术结合环境暴露分析，探讨职业和环境暴露与健康的关系及潜在机制。主持国家自然基金面上项目3项，省部级项目10余项；发表SCI论文74篇，获省科学技术奖3项，授权国家发明专利4项和新型实用专利2项。任《中华疾病控制杂志》、《安徽医科大学学报》、《环境卫生学杂志》等杂志编委，EP、ER和EES等期刊审稿专家。

研究方向：职业和环境暴露与健康

代表性科研项目：

[1]国家自然科学基金面上项目：母体肠道菌群SCFAs-胚胎GPR轴调控孕期双酚A暴露诱导的子代成年期肥胖易感性增加的研究（批准号：82073594），起止年月：2021/01-2024/12;

[2]国家自然科学基金面上项目：双酚A增加脂肪组织巨噬细胞神经酰胺从头合成介导肥胖衍生的胰岛素抵抗及其机制（批准号：81773467）,起止年月：2018/01-2021/12；

[3]国家自然科学基金面上项目：IL-17介导巨噬细胞极化对BPA诱导肥胖中脂肪组织炎症的调控及机制研究（批准号：81473015），起止年月：2015/01-2018/12。

[4]安徽高校协同创新项目：煤尘诱导肺上皮细胞亚群变化在肺炎症/纤维化中作用及靶向治疗研究（编号：GXXT-2022-065），子课题：生产性粉尘致肺部疾患中免疫代谢调控研究，负责人，起止年月：2023/01-2025/12。

代表性学术论文：

[1] Zhang W, Hong Y, Qiu YJ, Shen T*.Integrative genetic, single-cell and mechanistic dissection identifies bisphenol a as a causal driver of preeclampsia via fibroblast-derived IL-6/STAT3 signaling. Environ Pollut. Published online September 16, 2025. doi:10.1016/j.envpol.2025.127128. (IF:7.3,中科院2区

[2]Zhang X#, Zhao W#, Hu X#, Shen Y, Gan Y, Zou J, Zhou Y, Zhu T, Shen T*.Activation of Sirt1 protects from single-walled carbon nanotubes-induced pulmonary fibrosis by inhibiting alveolar macrophage senescence. Ecotoxicol Environ Saf. 2025; 302:118629. doi:10.1016/j.ecoenv.2025.118629. (IF:6.1,中科院1区)

[3]Hong X, Wang S, Zhang Q, Li L, Liu H, Yang H, Wu D, Liu X, Shen T*. Bisphenol A exacerbates colorectal cancer progression through enhancing ceramide synthesis. Toxicology. 2025 Feb;511:154054. doi: 10.1016/j.tox.2025.154054. (IF:4.8,中科院2区)

[4] Zhu J#, Zhang X#, Li L, Yang H, Liu H, Wu D, Liu Z, Liu B, Shen T*. C5a-C5aR1 axis mediates lung inflammation and fibrosis induced by single-walled carbon nanotubes via promoting neutrophils recruitment. Ecotoxicol Environ Saf. 2025 Jan 1;289:117627. doi: 10.1016/j.ecoenv.2024.117627. (IF:6.8,中科院1区)

[5] Xu Hong#, Yi Zhou#, Zhiyuan Zhu, Yuting Li, Zuo Li, Yuheng Zhang, Xinxin Hu, Fuhai Zhu, Yong Wang, Mingliang Fang, Yichao Huang*, Tong Shen*. Environmental endocrine disruptor Bisphenol A induces metabolic derailment and obesity via upregulating IL-17A in adipocytes, Environment International. 2023,172, 107759. doi.org/10.1016/j.envint. 2023.107759. (IF:11.8,中科院1区)

[6] Xiang Zhang#, Xinxin Hu#, Yuqing Zhang, Bin Liu, Haihong Pan, Zikai Liu, Zhuomeng Yao, Qixing Zhu, Changhao Wu, Tong Shen*. Impaired autophagy-accelerated senescence of alveolar type II epithelial cells drives pulmonary fibrosis induced by single-walled carbon nanotubes. Journal of Nanobiotechnology. 2023.2. (IF:10.2,中科院1区)

[7] Gengfu Wang#, Geng Xu#, Chao Zhang#, Azhu Han, Guobao Zhang, Liru Chen, Guodie Xie, Fangbiao Tao, Tong Shen*, Puyu Su*.Gestational bisphenol A exposure advances puberty onset in female offspring: Critical time window identification. Ecotoxicology and Environmental safety. 2023, 249, 114387. (IF:6.8,中科院1区)

[8] Xu Hong#, Gengfu Wang#, Xingcun Liu, Ming Wu, Xindong Zhang, Xiaohui Hua, Pengpeng Jiang, Sheng Wang, Song Tang, Xiaoming Shi, Yichao Huang*, Tong Shen*. Lipidomic biomarkers: Potential mediators of associations between urinary bisphenol A exposure and colorectal cancer. Journal of Hazardous Materials. 2022. 427(5): 127863. (IF:13.6,中科院1区)

[9] Xiang Zhang#, Jiaojiao Zhu#, Shuxin Yang#, Zhuomeng Yao, Sujuan Zhao, Yan Wang, Chengfan Zhou, Qixing Zhu, Tong Shen*. IL-4-activated C/EBPβ is involved in alveolar macrophage polarization towards the M2 phenotype during pulmonary fibrosis induced by single-walled carbon nanotubes. Environ Sci: Nano. 2022,9, 4233-4248

[10] Xiang Zhang, Min Luo, Jiaxiang Zhang, Zhuomeng Yao, Jiaojiao Zhu, Shuxin Yang, Qixing Zhu, Tong Shen*. Carbon nanotubes promote alveolar macrophages toward M2 polarization mediated epithelial-mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation. Nanotoxicology. 2021.15(5):588-604.

[11]Gengfu Wang,Yingpei Li,Yun Li,Jiaxiang Zhang,Chengfan Zhou,Changhao Wu,Qixing Zhu*,Tong Shen*.Maternal vitamin D supplementation inhibits bisphenol A-induced proliferation of Th17 cells in adult offspring. Food and Chemical Toxicology. 2020. 144: 111604.

[12] Luo SM，Li Y，Li YP，Zhu QX，Jiang JH，Wu CH，Shen T*.Gestational and lactational exposure to low-dose bisphenol A increases Th17 cells in mice offspring. Environmental Toxicology and Pharmacology. 2016. 47:149~158.

联系方式：shentong@ahmu.edu.cn